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Click on the phrases to see them in context. The original texts by Immanuel Kant and David Hume are available from the Gutenberg Projet.
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For it cannot be alleged that, instead of the laws of nature, laws of freedom may be introduced into the causality of the course of nature. In the same way, it is quite natural that, as the systematic unity of nature cannot be established as a principle for the empirical employment of reason, unless it is based upon the idea of an ens realissimum, as the supreme cause, we should regard this idea as a real object, and this object, in its character of supreme condition, as absolutely necessary, and that in this way a regulative should be transformed into a constitutive principle. For, when the explanation of natural phenomena happens to be difficult, we have constantly at hand a transcendental ground of explanation, which lifts us above the necessity of investigating nature; and our inquiries are brought to a close, not because we have obtained all the requisite knowledge, but because we abut upon a principle which is incomprehensible and which, indeed, is so far back in the track of thought as to contain the conception of the absolutely primal being. On the other hand, there must be in physical science an infinite number of conjectures, which can never become certainties; because the phenomena of nature are not given as objects dependent on our conceptions.