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Click on the phrases to see them in context. The original texts by Immanuel Kant and David Hume are available from the Gutenberg Projet.

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In this case, not only the series originated by this spontaneity, but the determination of this spontaneity itself to the production of the series, that is to say, the causality itself must have an absolute commencement, such that nothing can precede to determine this action according to unvarying laws.

 The attention is on the stretch: The posture of the mind is uneasy; and the spirits being diverted from their natural course, are not governed in their movements by the same laws, at least not to the same degree, as when they flow in their usual channel. 
From the inability of reason to establish this principle as a necessary law for the acquisition of all experience, he inferred the nullity of all the attempts of reason to pass the region of the empirical.